Wednesday, September 28, 2016

Scientists implanting blood vessels in lambs – NU.nl

the animals were a part of their pulmonary artery is replaced by a laboratory-created blood vessel in the body continued to grow.

The technique can in the future lead to new ways to help children with heart defects to treat.

That report American researchers in the scientific journal Nature Communications.

Sheep

scientists created the kunstbloedvaten with the help of skin cells of sheep, from which stem cells were grown.

These cells were in the laboratory was modified in such a way that they are in the form of blood vessels began to grow. After five weeks, the blood vessels, stripped of all cells, leaving only a kind of skeleton remained. With this ‘bloedvatskeletten’ was then a piece of the pulmonary artery is replaced by several lambs.

Mature

That operation succeeded very well. The lambs survived the surgery and grew up to be adult sheep.

After the implantation is started, there are body cells of the animals on the kunstbloedvaten to grow, so the bodies were not disposed of. There were, as it were, new blood vessels on the bloedvatskeletten’, which as a result meegroeiden with the body.

heart surgery

According to principal investigator Robert Tranquillo similar vessels in the future may be used in heart surgeries, for example, if arteries are to be adopted in children.

Now, young patients in whom an artery is attached, often many surgeries to undergo because the sutures do not grow with their bodies.

The new tested kunstbloedvaten can in theory grow. “We make use of a natural process in the body that of the bloedvatskeletten again, alive tissue,” says Tranquillo on news site Phys.org. “Hopefully we can do this within a few years of testing on people.”

By: NU.nl/Dennis Rijnvis

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